Delico’s Nursery will focus on Dali Delico (Masakazu Morita), a vampire given a mission by the highest governing body for vampires. Despite the group’s importance, he refuses. Gerhard Fra (Katsuyuki Konishi), Dino Classico (Takuya Satou), and Henrique Lorca (Hiro Shimono), all members of the council, try to persuade Dali by visiting him in person.
When they meet Dali, he is handling several children. Together, the four work on performing the jobs and duties assigned to them and raising their children.
In addition to the four adult vampires in Delico’s Nursery, there are six children in the show. Uru Delico (Rina Hidaka), Raphael Delico (Konomi Kohara), Angelico Fra (Ayasa Ito), Lucia Lorca (Yu Wakui), Yelena Lorca (Sanae Fuku), and Theodore Classico (Chika Anzai).